CELLUBIOME — Daily Gut-Mito Support

500 mg urolithin A (≥99% pure) + 500 mg enteric-coated tributyrin

The daily gut formula built around these two molecules — not a probiotic blend. Targeted gut-barrier and mitochondrial support, fully disclosed — and bottled in glass.*

$110.00 one-time · $93.50/month with Subscribe & Save (15% off) · 60 enteric-coated capsules · 30-day supply · Free US shipping · 30-day guarantee

Supplement Facts

Serving Size: 2 Capsules · Servings Per Container: 30

Mitochondrial Renewal — 500 mg Urolithin A

Studied in published human trials at 500 mg to support mitochondrial recycling (mitophagy) and cellular energy efficiency.

Urolithin A (≥99% Purity) — 500 mg

Gut Barrier Support — 500 mg Tributyrin

A stable butyrate precursor that supports intestinal barrier integrity and microbiome-related gut resilience.

Tributyrin (Butyrate Precursor) — 500 mg

Other Ingredients: Vegetable Capsule (Hypromellose), Enteric Coating (Hypromellose, PEG), Purified Water.

Research-aligned doses. Enteric-protected delivery. No proprietary blends. Packaged in glass.

cGMP Made · 3rd-Party Tested · Glass Bottle · Full Disclosure · Transparent doses · Glass bottle

Over Time

2 Weeks

Daily routine established — enteric capsules designed for intestinal release* Butyrate begins supporting intestinal barrier cells* Initial cellular recycling support via mitophagy activation*

4 Weeks

Improved gut barrier resilience* More consistent mitochondrial energy efficiency* Reduction in digestive variability*

8 Weeks

Strengthened gut–mitochondria signaling* Enhanced cellular renewal dynamics* Greater systemic resilience*

3 Months

Compounded support for mitochondrial function* Sustained intestinal barrier integrity* Long-term biological stability foundation*

Why this isn't another probiotic

CELLUBIOME: 500 mg urolithin A + 500 mg enteric tributyrin. Both actives at research-aligned doses. Enteric-coated for intestinal release. Third-party tested, every dose disclosed. $93.50/mo with Subscribe & Save.

Single-molecule urolithin A products: same 500 mg urolithin A, but no butyrate or gut-barrier layer. About $99 for a 30-day supply.

Standard probiotic / gut blends: live strains — no urolithin A, no direct butyrate. Blend-level dosing (AFU totals). Depends on what your microbiome does with it.

500 mg urolithin A dose aligned with Singh et al., Cell Reports Medicine (2022). As of August 2026, we haven't found another formula that pairs urolithin A with tributyrin.

The Science

The Gut–Mitochondria Axis

The gut barrier and mitochondrial function are biologically interconnected. Disruption in either system can amplify inflammation, impair cellular energy production, and accelerate biological aging.3

CELLUBIOME pairs Urolithin A — shown in a 2022 randomized, placebo-controlled human trial to induce a molecular signature of improved mitochondrial and cellular health1 and to improve muscle endurance in middle-aged adults2 — with Tributyrin, a stable triglyceride form of butyrate, the short-chain fatty acid colonocytes use as their primary energy source and a key regulator of intestinal barrier integrity.3

References

  1. Singh A, et al. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults. Cell Reports Medicine. 2022.
  2. Liu S, et al. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults: A Randomized Clinical Trial. JAMA Network Open. 2022.
  3. Hamer HM, et al. Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther. 2008;27(2):104–119.

Testing & Standards

Tested. Disclosed. Traceable.

Third-party tested — every lot is tested for identity and potency.

CGMP manufacturing — produced in a CGMP-compliant facility.

No proprietary blends — every ingredient and every dose on the label.

Glass packaging — inert glass bottles, not plastic.

Current lot 150126 — finished-product results: urolithin A tested at 548.15 mg/2 capsules (label claim 500 mg per serving) · tributyrin 530.80 mg/2 capsules (label claim 500 mg per serving) · heavy-metals and microbial panels reported. View Full Certificate of Analysis →

Certificate of Analysis — finished product, Lot 150126

Analytical/Chemical Certificate of Analysis (finished product). Tested by Delta Labs of South Florida Corp. (ISO/IEC 17025:2017 — PJLA Accreditation # 114871). Lab ID 22388 · Lot 150126 · Sample received 01/14/26.

TestMethodReported resultSpecificationStatus
Assay Urolithin AUrolithin A via HPLC548.15 mg/2 capsulesNLT 500 mg/2 capsulesMeets specification
Assay TributyrinTributyrin via GC530.80 mg/2 capsulesNLT 500 mg/2 capsulesMeets specification
Lead (Pb)Heavy Metals via ICP-MS0.0540 mcg/servingReport Results in mcg/servingReported
Arsenic (As)Heavy Metals via ICP-MS0.0414 mcg/servingReport Results in mcg/servingReported
Mercury (Hg)Heavy Metals via ICP-MS0.0000 mcg/servingReport Results in mcg/servingReported
Cadmium (Cd)Heavy Metals via ICP-MS0.0547 mcg/servingReport Results in mcg/servingReported
ChromiumChromium via ICP-MS1.40 mcg/servingReport ResultReported
Total Plate CountUSP 43 <61>100 CFU/gNMT 10,000 CFU/gMeets specification
Total Yeast and MoldUSP 43 <62>60 CFU/gNMT 1,000 CFU/gMeets specification
Staphylococcus aureusUSP 43 <61>/<62>NegativeNegativeMeets specification

This certificate reports the tests listed below, performed on a finished-product sample of CELLUBIOME lot 150126. It does not cover tests that are not listed on the report.

View Full Certificate of Analysis → · Original report image

About our quality standards →

Product Images

CELLUBIOME bottle — 500 mg urolithin A + 500 mg enteric tributyrin, 60 enteric-coated capsules CELLUBIOME supplement facts — urolithin A ≥99% (500 mg) and tributyrin (500 mg), fully disclosed CELLUBIOME third-party lab certificate of analysis — Lot 150126 Two actives at 500 mg each — urolithin A plus enteric-coated tributyrin Enteric delivery, designed to release in the intestine rather than the stomach CELLUBIOME glass bottle and packaging

Frequently Asked Questions

How is CELLUBIOME different from a probiotic?

CELLUBIOME is not a probiotic. Probiotics add live bacteria. CELLUBIOME pairs urolithin A with enteric tributyrin to support gut-barrier integrity and mitochondrial renewal — two pathways most probiotic blends do not address.

Can I take CELLUBIOME with CELLUNAD+?

Yes. CELLUBIOME and CELLUNAD+ are designed to work together as a daily system. CELLUNAD+ supports NAD+ replenishment; CELLUBIOME supports the gut-mitochondria axis. There is no ingredient overlap.

Why does enteric delivery matter?

Standard capsules can degrade in stomach acid. Enteric coating is designed to protect urolithin A and tributyrin until they reach the intestine, where absorption and barrier support occur.

Why 500 mg Urolithin A?

500 mg aligns with the dose used in published human studies of urolithin A and mitochondrial-related biomarkers (Singh et al., Cell Reports Medicine, 2022).

Why tributyrin instead of butyrate salts?

Tributyrin is a more stable precursor that supports downstream butyrate delivery, rather than relying on butyrate salts that can break down before reaching the intestine.

How long should I evaluate CELLUBIOME?

Evaluate CELLUBIOME over 8–12 weeks of daily use.* Gut-barrier and mitochondrial adaptation is measured in weeks, not days.

Can I take CELLUBIOME with food?

Yes. Take with or without food. Consistency matters more than timing.

Why does CELLUBIOME cost more than single-ingredient urolithin A products?

At the same 500 mg dose, single-molecule urolithin A products typically run about $99 for a 30-day supply. CELLUBIOME includes the same 500 mg of urolithin A plus 500 mg of enteric-coated tributyrin for gut-barrier support, so one formula covers both pathways — $93.50/month with Subscribe & Save.

How does Subscribe & Save work?

Subscribe & Save is $93.50/month — 15% off the one-time price — billed and delivered monthly. Every order includes free US shipping and the 30-day guarantee. You can skip a delivery or cancel anytime at agerevive.com/manage-subscription.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.